Publications on BSD‑500 & BSD‑2000
Hyperthermia clinical studies
In the table below you will find Hyperthermia clinical studies over the past three decades on the effectiveness of adding superficial and regional hyperthermia to radiation therapy and/or chemotherapy.
Year | Tumor | Author | Title | No. of Patients | Method | System | Journal | Abstract | |
---|---|---|---|---|---|---|---|---|---|
2023 | Pancreatic Cancer | Issels | Regional hyperthermia with cisplatin added to gemcitabine versus gemcitabine in patients with resected pancreatic ductal adenocarcinoma: The HEAT randomised clinical trial (2023) | 117 | CT+HT | BSD-2000/3D-MRI | European Journal of Cancer | PR | |
2023 | Not specified | Ademaj | A patterns of care analysis of hyperthermia in combination with radio(chemo)therapy or chemotherapy in European clinical centers (2023) | CT/RCT/RT+HT | BSD-2000/3D-MRI, BSD-500 | Strahlenther Onkol | OT | ||
2023 | Bladder Cancer | Ott | The Emerging Evidence Supporting Integration of Deep Regional Hyperthermia With Chemoradiation in Bladder Cancer (2023) | RCT+HT | BSD-2000/3D-MRI | Semin Radiat Oncol | RV | ||
2022 | Bladder Cancer | Riesterer | Tetramodal therapy with transurethral resection followed by chemoradiation in combination with hyperthermia for muscle-invasive bladder cancer: early results of a multicenter phase IIB study (2022) | 27 | RCT+HT | BSD-2000 3D | IJH | NR | |
2022 | Breast Cancer | De-Colle | Radiotherapy and hyperthermia for breast cancer patients at high risk of recurrence (2022) | 191 | RT+HT | SA-115/BSD-500 | IJH | NR | |
2022 | Rectal Cancer | Schem | Long-Term Outcome in a Phase II Study of Regional Hyperthermia Added to Preoperative Radiochemotherapy in Locally Advanced and Recurrent Rectal Adenocarcinomas (2022) | 49 | RCT+HT | BSD 2000 | Cancers | NR | |
2022 | Not specified | Ademaj | Clinical Evidence for Thermometric Parameters to Guide Hyperthermia Treatment (2022) | Including BSD-2000/3D-MRI, BSD-500 | Cancers | RV | |||
2022 | Cervical Cancer | Gao | Acute and long-term toxicity in patients undergoing induction chemotherapy followed by thermoradiotherapy for advanced cervical cancer (2022) | 105 | CT+RT+HT | BSD-2000 3D | IJH | NR | |
2022 | Breast Cancer | Chichel | Thermal Boost Combined with Interstitial Brachytherapy in Early Breast Cancer Conserving Therapy-Initial Group Long-Term Clinical Results and Late Toxicity (2022) | 32 | RT+HT | BSD-500 | Journal of Personalized Medicine | NR | |
2021 | Prostate Cancer | Beck | Salvage-Radiation Therapy and Regional Hyperthermia for Biochemically Recurrent Prostate Cancer after Radical Prostatectomy (Results of the Planned Interim Analysis) (2021) | 50 | SRT+HT | BSD-2000/3D-MRI | Cancers | NR | |
2021 | Sarcoma | Willner | Neoadjuvant concurrent chemoradiotherapy with and without hyperthermia in retroperitoneal sarcomas: feasibility, efficacy, toxicity, and long-term outcome (2021) | 15 | CRT+HT | BSD-2000/3D-MRI | Strahlenther Onkol | NR | |
2021 | Breast Cancer | Stoetzer | Post-Neoadjuvant Gemcitabine and Cisplatin with Regional Hyperthermia for Patients with Triple-Negative Breast Cancer and Non-pCR after Neoadjuvant Chemotherapy: A Single-Institute Experience (2021) | 53 | CT+HT | BSD 2000 | Breast Care | NR | |
2021 | Pediatric Cancer | Nadobny | Improved patient-specific hyperthermia planning based on parametrized electromagnetic and thermal models for the SIGMA-30 applicator (2021) | CT+HT | BSD 2000/3D | IJH | OT | ||
2021 | Bladder Cancer | Brummelhuis | Long-Term Experience with Radiofrequency-Induced Hyperthermia Combined with Intravesical Chemotherapy for Non-Muscle Invasive Bladder Cancer (2021) | 274 | RF-CHT | Synergo SB-TS 101 | Cancers | NR | |
2021 | Rectal Cancer | Gani | Deep regional hyperthermia with preoperative radiochemotherapy in locally advanced rectal cancer, a prospective phase II trial (2021) | 78 | RT+HT | BSD-2000/3D, BSD-2000 3D/MRI | Radiother Oncol | NR | |
2021 | Soft-tissue sarcoma | Issels | Immune infiltrates in patients with localized high-risk soft tissue sarcoma treated with neoadjuvant chemotherapy without or with regional hyperthermia: A translational research program of the EORTC 62961-ESHO 95 randomised clinical trial (2021) | 109 | CT+HT | BSD-2000/3D, BSD-2000 3D/MRI | European Journal of Cancer | PR | |
2021 | Soft-tissue sarcoma | Lindner | Perioperative chemotherapy and regional hyperthermia for high-risk adult-type soft tissue sarcomas (2021) | CT+HT | BSD-2000/3D, BSD-2000 3D/MRI | European Journal of Cancer | RV | ||
2021 | Rectal cancers | Ott | Neoadjuvant Chemoradiation Combined with Regional Hyperthermia in Locally Advanced or Recurrent Rectal Cancer (2021) | 111 | CT-RT+HT | BSD-2000/3D, BSD-2000 3D/MRI | Cancers | NR | |
2021 | Cervical Cancer | VilasBoas-Ribeiro | MR Thermometry Accuracy and Prospective Imaging-Based Patient Selection in MR-Guided Hyperthermia Treatment for Locally Advanced Cervical Cancer (2021) | 14 | RT+HT | BSD-2000-3D MR | Cancers | OT | |
2020 | Various, e.g., anal, rectal, bladder cancer, and sarcomas | Paulides | Recent technological advancements in radiofrequency and microwave-mediated hyperthermia for enhancing drug delivery (2020) | Regional, superficial, and deep HT | BSD-500, BSD-2000, BSD-2000 3D, BSD-2000 3D/MR, Sigma-30/40/60 | Advanced Drug Delivery Reviews | RV | ||
2020 | General | Datta | Integrating Loco-Regional Hyperthermia Into the Current Oncology Practice: SWOT and TOWS Analyses (2020) | ReRT+HT, CTRT+HT | Frontiers in Oncology | OT | |||
2020 | Bladder cancer | Dunst | Organerhaltende Therapie des Harnblasenkarzinoms (2020) | RCT+RHT | Strahlenther Onkol | OT | |||
2020 | Breast Cancer | Hader | Differences of the Immune Phenotype of Breast Cancer Cells after Ex Vivo Hyperthermia by Warm-Water or Microwave Radiation in a Closed-Loop System Alone or in Combination with Radiotherapy (2020) | RT+HT | Experimental device / water bath | Cancers | OT | ||
2020 | General | Hader | Immune biological rationales for the design of combined radio- and immunotherapies (2020) | RT+HT | Cancer Immunology, Immunotherapy | RV | |||
2020 | Soft Tissue Sarcoma | Unsoeld | MR Thermometry Data Correlate with Pathological Response for Soft Tissue Sarcoma of the Lower Extremity in a Single Center Analysis of Prospectively Registered Patients (2020) | 11 | R/CT+LHT | BSD-2000 3D/MR | Cancers | NR | |
2020 | Soft Tissue Sarcoma | Bücklein | Ifosfamide, Carboplatin, and Etoposide (ICE) in Combination with Regional Hyperthermia as Salvage Therapy in Patients with Locally Advanced Nonmetastatic and Metastatic Soft-Tissue Sarcoma (2020) | 110 | ICE+RHT | BSD-2000 | Sarcoma | NR | |
2020 | Not specified | Gaipl | Editorial: Radioimmunotherapy-Translational Opportunities and Challenges (2020) | Radioimmunotherapy | Frontiers in Oncology | OT | |||
2020 | Not specified | Adibzadeha | Systematic review of pre-clinical and clinical devices for magnetic resonance-guided radiofrequency hyperthermia (2020) | MR-guided RF HT | BSD-2000-3D-MRI | IJH | RV | ||
2020 | Glioma | Schneider | Radiosensitization of high-grade gliomas through induced hyperthermia: Review of clinical experience and the potential role of MR-guided focused ultrasound (2020) | HT+RT | Radiother Oncol | RV | |||
2020 | Rhabdomyosarcoma | Issels | Systemic antitumor effect by regional hyperthermia combined with low-dose chemotherapy and immunologic correlates in an adolescent patient with rhabdomyosarcoma - a case report (2020) | 1 | CT+HT | BSD-2000 | IJH | OT | |
2019 | Bladder Cancer | Merten | Long‐Term Experience of Chemoradiotherapy Combined with Deep Regional Hyperthermia for Organ Preservation in High‐Risk Bladder Cancer (Ta, Tis, T1, T2) (2019) | 79 | RCT+HT | BSD-2000-3D | The Oncologist | NR | |
2019 | Breast Cancer | De-Colle | Hyperthermic chest wall re-irradiation in recurrent breast cancer: a prospective observational study (2019) | 20 | RT+HT | BSD‑500 | Strahlenther Onkol | NR | |
2018 | Soft Tissue Sarcoma | Issels | Effect of Neoadjuvant Chemotherapy Plus Regional Hyperthermia on Long-term Outcomes Among Patients With Localized High-Risk Soft Tissue Sarcoma. The EORTC 62961-ESHO 95 Randomized Clinical Trial (2018) | 341 | CT vs. CT+HT |
BSD‑2000 | JAMA Oncol | PR | |
2018 | Rectal Cancer | Zwirner | External validation of a rectal cancer outcome prediction model with a cohort of patients treated with preoperative radiochemotherapy and deep regional hyperthermia (2018) | 86 | RCT+HT | BSD‑2000 | IJH | NR | |
2014 | Soft Tissue Sarcoma | Angele | Effectiveness of regional hyperthermia with chemotherapy for high-risk retroperitoneal and abdominal soft-tissue sarcoma after complete surgical resection: a subgroup analysis of a randomized phase-III multicenter study. (2014) | 341 | CT vs. CT+HT |
BSD‑2000 | Ann Surg Oncol | PR | |
2013 | Pancreatic Cancer | Tschoep-Lechner | Gemcitabine and cisplatin combined with regional hyperthermia as second-line treatment in patients with gemcitabine-refractory advanced pancreatic cancer. (2013) | 23 | CT+HT | BSD‑2000 | IJH | NR | |
2012 | Cervical Cancer | Westermann | Long-term survival data of triple modality treatment of stage IIB-III-IVA cervical cancer with the combination of radiotherapy, chemotherapy and hyperthermia - an update. (2012) | 68 | RT+HT | BSD‑2000 | IJH | NR | |
2012 | Rectal Cancer | Schroeder | Pathological complete response and sphincter-sparing surgery after neoadjuvant radiochemotherapy with regional hyperthermia for locally advanced rectal cancer compared with radiochemotherapy alone. (2012) | 106 | RCT vs. RCT+HT |
BSD‑2000 | IJH | NR | |
2012 | Cervical Cancer | Heijkoop | Neoadjuvant chemotherapy followed by radiotherapy and concurrent hyperthermia in patients with advanced-stage cervical cancer: a retrospective study (2012) | 43 | RCT+HT | BSD‑2000 | IJH | NR | |
2014 | Cervical Cancer | Heijkoop | Results of concurrent chemotherapy and hyperthermia in patients with recurrent cervical cancer after previous chemoradiation (2014) | 38 | Re-CT+HT | BSD‑2000 | IJH | NR | |
2011 | Pancreatic Cancer | Maluta | Regional hyperthermia combined with chemoradiotherapy in primary or recurrent locally advanced pancreatic cancer : an open-label comparative cohort trial (2011) | 68 | RCT+HT | BSD‑2000 | Strahlenther Onkol | NR | |
2010 | Ovarian Cancer | Fotopoulou | Regional abdominal hyperthermia combined with systemic chemotherapy for the treatment of patients with ovarian cancer relapse: Results of a pilot study (2010) | 36 | CT+HT | BSD‑2000 | IJH | NR | |
2010 | Soft Tissue Sarcoma | Issels | Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study. (2010) | 341 | CT vs. CT+HT |
BSD‑2000 | Lancet Oncol | PR | |
2010 | Rectal Cancer | Maluta | Regional hyperthermia added to intensified preoperative chemo-radiation in locally advanced adenocarcinoma of middle and lower rectum (2010) | 76 | RCT+HT | BSD‑2000 | IJH | NR | |
2010 | Soft Tissue Sarcoma | Schlemmer | Thermochemotherapy in patients with extremity high-risk soft tissue sarcomas (HR-STS) (2010) | 47 | RCT+HT | BSD‑2000 | IJH | NR | |
2009 | Bladder Cancer | Wittlinger | Quadrimodal treatment of high-risk T1 and T2 bladder cancer: transurethral tumor resection followed by concurrent radiochemotherapy and regional deep hyperthermia (2009) | 45 | RCT+HT | BSD‑2000 | Radiother Oncol | NR | |
2009 | Cervical Cancer | Franckena | Radiotherapy and hyperthermia for treatment of primary locally advanced cervix cancer: results in 378 patients (2009) | 378 | RT+HT | BSD‑2000 | IJROBP | NR | |
2008 | Rectal Cancer | Milani | Radiochemotherapy in combination with regional hyperthermia in preirradiated patients with recurrent rectal cancer (2008) | 24 | RCT+RHT | BSD‑2000 | Strahlenther Onkol | NR | |
2008 | Cervical Cancer | Franckena | Long-term improvement in treatment outcome after radiotherapy and hyperthermia in locoregionally advanced cervix cancer: an update of the Dutch Deep Hyperthermia Trial. (2008) | 114 | RT vs. RT+HT |
BSD‑2000 | IJROBP | PR | |
2007 | Prostate Cancer | Maluta | Conformal radiotherapy plus local hyperthermia in patients affected by locally advanced high risk prostate cancer: preliminary results of a prospective phase II study (2007) | 144 | CRT+HT | BSD‑2000 | IJH | NR | |
2007 | Vaginal Cancer | Aktas | Concomitant radiotherapy and hyperthermia for primary carcinoma of the vagina: a cohort study. (2007) | 44 | RT+HT | BSD‑2000 | Eur J Obstet | NR | |
2006 | Cervical Cancer | Sreenivasa | Radiochemotherapy combined with regional pelvic hyperthermia induces high response and resectability rates in patients with nonresectable cervical cancer > or =FIGO IIB "bulky". (2006) | 32 | RCT+HT | BSD‑2000 | IJROBP | NR | |
2006 | Ovarian Cancer | Jones | Intra-peritoneal cisplatin and whole abdomen hyperthermia for relapsed ovarian carcinoma (2006) | 41 | CT+HT | BSD‑2000 | IJH | NR | |
2005 | Cervical Cancer | Westermann | First results of triple-modality treatment combining radiotherapy, chemotherapy, and hyperthermia for the treatment of patients with stage IIB, III, and IVA cervical carcinoma. (2005) | 68 | RCT+HT | BSD‑2000 | Cancer | NR | |
2005 | Ovarian Cancer | Hahn | Prospective assessment of quality of life in ovarian cancer patients receiving whole abdomen hyperthermia and liposomal doxorubicin. (2005) | 32 | CT+HT | BSD‑2000 | IJH | NR | |
2005 | Ovarian Cancer | Alvarez Secord | Phase I/II trial of intravenous Doxil and whole abdomen hyperthermia in patients with refractory ovarian cancer. (2005) | 30 | CT+HT | BSD‑2000 | IJH | NR | |
2005 | Prostate Cancer | Tilly | Regional hyperthermia in conjunction with definitive radiotherapy against recurrent or locally advanced prostate cancer T3 pN0 M0. (2005) | 22 | RT+HT | BSD‑2000 | Strahlenther Onkol | NR | |
2004 | Rectal Cancer | Hildebrandt | Regional pelvic hyperthermia as an adjunct to chemotherapy (oxaliplatin, folinic acid, 5-fluorouracil) in pre-irradiated patients with locally recurrent rectal cancer: a pilot study. (2004) | 9 | RT+HT | BSD‑2000 | IJH | NR | |
2004 | Soft Tissue Sarcoma | Fiegl | Ifosfamide, carboplatin and etoposide (ICE) as second-line regimen alone and in combination with regional hyperthermia is active in chemo-pre-treated advanced soft tissue sarcoma of adults. (2004) | 20 | CT+HT | BSD‑2000 | IJH | NR | |
2003 | Rectal Cancer | Juffermans | Reirradiation and hyperthermia in rectal carcinoma: a retrospective study on palliative effect. (2003) | 54 | RT+HT | BSD‑2000 | Cancer | NR | |
2003 | Cervical Cancer | Jones | A pilot Phase II trial of concurrent radiotherapy, chemotherapy, and hyperthermia for locally advanced cervical carcinoma. (2003) | 12 | RT+HT | BSD‑2000 | Cancer | NR | |
2003 | Prostate Cancer | Kalapurakal | Efficacy of irradiation and external hyperthermia in locally advanced, hormone-refractory or radiation recurrent prostate cancer: a preliminary report. (2003) | 13 | RT+HT | BSD‑2000 | IJROBP | NR | |
2003 | Cervical Cancer | Van der Zee | The Dutch Deep Hyperthermia Trial: results in cervical cancer (2003) | 114 | RT vs. RT+HT |
BSD‑2000 | IJH | PR | |
2003 | Pediatric Tumors | Wessalowski | An approach for cure: PEI-chemotherapy and regional deep hyperthermia in children and adolescents with unresectable malignant tumors (2003) | 39 | CT+HT | BSD‑2000 | Klin Padiatr | NR | |
2013 | Germ Cell Tumors | Wessalowski | Regional deep hyperthermia for salvage treatment of children and adolescents with refractory or recurrent non-testicular germ-cell tumours: an open-label, non-randomised, single-institution, phase 2 study (2013) | 44 | CT+HT | BSD‑2000 | Lancet Oncol | NR | |
2002 | Soft Tissue Sarcoma | Wendtner | Response to neoadjuvant chemotherapy combined with regional hyperthermia predicts long-term survival for adult patients with retroperitoneal and visceral high-risk soft tissue sarcomas. (2002) | 58 | CT+HT | BSD‑2000 | JCO | NR | |
2001 | Soft Tissue Sarcoma | Issels | Neoadjuvant chemotherapy combined with regional hyperthermia (RHT) for locally advanced primary or recurrent high-risk adult soft-tissue sarcomas (STS) of adults: long-term results of a phase II study. (2001) | 59 | CT+HT | BSD‑2000 | Eur J Cancer | NR | |
2001 | Germ Cell Tumors | Schneider | Treatment of recurrent malignant sacrococcygeal germ cell tumors: analysis of 22 patients registered in the German protocols MAKEI 83/86, 89, and 96. (2001) | 22 | CT+HT | BSD‑2000 | JCO | NR | |
2001 | Soft Tissue Sarcoma | Wendtner | Treatment of primary, recurrent or inadequately resected high-risk soft-tissue sarcomas (STS) of adults: results of a phase II pilot study (RHT-95) of neoadjuvant chemotherapy combined with regional hyperthermia. (2001) | 54 | RCT+HT | BSD‑2000 | Eur J Cancer | NR | |
2001 | Prostate Cancer | Kalapurakal | Re-irradiation and external hyperthermia in locally advanced, radiation recurrent, hormone refractory prostate cancer: a preliminary report. (2001) | 3 | RT+HT | BSD‑2000 | Br J Radiol | NR | |
2000 | Rectal Cancer | Anscher | A pilot study of preoperative continuous infusion 5-fluorouracil, external microwave hyperthermia, and external beam radiotherapy for treatment of locally advanced, unresectable, or recurrent rectal cancer. (2000) | 15 | CT+HT | BSD‑2000 | IJROBP | NR | |
2000 | Cervical Cancer | Van der Zee | Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumors: a prospective, randomized, multicentre trial. Dutch Deep Hyperthermia Group (2000) | 114 | RT vs. RT+HT |
BSD‑2000 | Lancet | PR | |
2000 | Rectal Cancer | Rau | Preoperative radiochemotherapy in locally advanced or recurrent rectal cancer: regional radiofrequency hyperthermia correlates with clinical parameters. (2000) | 55 | RCT+HT | BSD‑2000 | IJROBP | NR | |
2000 | Bladder Cancer | Van der Zee | Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumors: a prospective, randomized, multicentre trial. Dutch Deep Hyperthermia Group (2000) | 101 | CT+RT vs. RT+HT |
BSD‑2000 | Lancet | PR | |
2000 | Rectal Cancer | Van der Zee | Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumors: a prospective, randomized, multicentre trial. Dutch Deep Hyperthermia Group (2000) | 143 | RT vs. RT+HT |
BSD‑2000 | Lancet | PR | |
1999 | Soft Tissue Sarcoma | Prosnitz | The treatment of high-grade soft tissue sarcomas with preoperative thermoradiotherapy. (1999) | 97 | RT+HT | BSD‑2000 | IJROBP | NR | |
1999 | Cervical Cancer | de Wit | A phase I/II study of combined weekly systemic cisplatin and locoregional hyperthermia in patients with previously irradiated recurrent carcinoma of the uterine cervix. (1999) | 19 | CT+HT | BSD‑2000 | Br J Radiol | NR | |
1998 | Germ Cell Tumors | Wessalowski | Hyperthermia for the treatment of patients with malignant germ cell tumors: a phase I/II study in ten children and adolescents with recurrent or refractory tumors (1998) | 7 | CT+HT | BSD‑2000 | Cancer | NR | |
1998 | Rectal Cancer | Rau | Preoperative hyperthermia combined with radiochemotherapy in locally advanced rectal cancer: a phase II clinical trial. (1998) | 37 | RCT+HT | BSD‑2000 | Ann Surg Oncol | NR | |
1997 | Germ Cell Tumors | Wessalowski | Treatment results in children and adolescents with loco-regional recurrences of abdominal germ cell tumors (GCTs): a pilot-study with PEI chemotherapy and regional deep hyperthermia (RHT) in comparison to a matched cohort (1997) | 9 | CT+HT | BSD‑2000 | Klin Padiatr | NR | |
1997 | Prostate Cancer | Anscher | Combined external beam irradiation and external regional hyperthermia for locally advanced adenocarcinoma of the prostate. (1997) | 30 | RT+HT | BSD‑2000 | IJROBP | NR | |
1996 | Deep Tumors | Myerson | A phase I/II study to evaluate radiation therapy and hyperthermia for deep-seated tumours: a report of RTOG 89-08. (1996) | 66 | RT+HT | BSD‑2000 | IJH | NR | |
1994 | Soft Tissue Sarcoma | Scully | Clinical outcome after neoadjuvant thermoradiotherapy in high grade soft tissue sarcomas (1994) | 40 | RT+HT | BSD‑2000 | J Surg Oncol | NR | |
1994 | Head & Neck Tumor | Valdagni | Radical radiation alone versus radical radiation plus microwave hyperthermia for N3 (TNM-UICC) neck nodes: a prospective randomized clinical trial. (1994) | 44 | RT vs. RT+LHT |
BSD‑500 | IJROBP | PR | |
1991 | Prostate Cancer | Kaplan | Secondary external-beam radiotherapy and hyperthermia for local recurrence after 125-iodine implantation in adenocarcinoma of the prostate (1991) | 6 | RT+HT | BSD‑2000 | IJROBP | NR | |
1991 | Genitourinary Cancer | Petrovich | Regional hyperthermia in patients with recurrent genitourinary cancer. (1991) | 53 | RT vs. RT+HT |
BSD‑2000 | Am J Clin Oncol | NR | |
1990 | Soft Tissue Sarcoma | Issels | Ifosfamide plus etoposide combined with regional hyperthermia in patients with locally advanced sarcomas: a phase II study. (1990) | 40 | CT+HT | BSD‑2000 | JCO | NR | |
2019 | Rectal Cancer | Ott | Chemoradiotherapy with and without deep regional hyperthermia for squamous cell carcinoma of the anus (2019) | 112 | RCT vs RCT + HT |
BSD‑2000 | Strahlenther Onkol | NR | |
2016 | Breast Cancer | Auoragh | Re-irradiation of the chest wall for local breast cancer recurrence : Results of salvage brachytherapy with hyperthermia. (2016) | 18 | Re-RT + IHT | BSD‑500 | Strahlenther Onkol | NR | |
2002 | Head & Neck Tumor | Geiger | Pulsed-dose rate brachytherapy with concomitant chemotherapy and interstitial hyperthermia in patients with recurrent head-and-neck cancer. (2002) | 15 | Re-RT + CT+IHT |
BSD‑500 | Brachytherapy | NR | |
2000 | Soft Tissue Sarcoma | Zschaeck | Neoadjuvant chemotherapy plus radiation versus chemotherapy plus regional hyperthermia in high-grade soft tissue sarcomas: a retrospective comparison. (2000) | 61 | CT+RT vs. CT+HT |
BSD‑2000 | Brachytherapy | NR | |
2019 | Cervical Cancer | Datta | Efficacy and Safety Evaluation of the Various Therapeutic Options in Locally Advanced Cervix Cancer: A Systematic Review and Network Meta-Analysis of Randomized Clinical Trials (2019) | 9894 | Various | IJROBP | MA | ||
2016 | Breast Cancer (recurrent) | Datta | Hyperthermia and Radiation Therapy in Locoregional Recurrent Breast Cancers: A Systematic Review and Meta-analysis. (2016) | 627 | Various | IJROBP | MA | ||
2016 | Head & Neck Tumor | Datta | Hyperthermia and radiotherapy in the management of head and neck cancers: A systematic review and meta-analysis. (2016) | 451 | Various | IJH | MA | ||
2017 | Cervical Cancer | Datta | Concurrent chemoradiotherapy vs. radiotherapy alone in locally advanced cervix cancer: A systematic review and meta-analysis. (2017) | 2445 | Various | Gynecol Oncol | MA | ||
2016 | Cervical Cancer | Datta | Hyperthermia and radiotherapy with or without chemotherapy in locally advanced cervical cancer: a systematic review with conventional and network meta-analyses. (2016) | 807 | Various | IJH | MA | ||
2015 | Summary Review | Cihoric | Hyperthermia-related clinical trials on cancer treatment within the ClinicalTrials.gov registry. (2015) | Various | IJH | RV | |||
2013 | Summary Review | Overgaard | The heat is (still) on--the past and future of hyperthermic radiation oncology. (2013) | Various | Radiother Oncol | RV | |||
2002 | Summary Review | Wust | Hyperthermia in combined treatment of cancer. (2002) | Various | IJH | RV | |||
2016 | Summary Review | Issels | Hallmarks of hyperthermia in driving the future of clinical hyperthermia as targeted therapy: translation into clinical application. (2016) | Various | IJH | RV |
- CHT
- Chemothyperthermia
- HT
- Hyperthermia
- IHT
- Interstitial Hyperthermia
- LHT
- Local Hyperthermia
- RCT
- RadioChemotherapy
- RT
- Radiotherapy